Dipyridamole thallium 201 imaging. How safe is it?

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Dipyridamole thallium 201 imaging. How safe is it?

D ipyridamole thallium 201 scintigraphy is increasingly being used as an alternative to exercise scintigraphy for detection of coronary artery disease and risk stratification.1,2 Intravenous infusion of 0.56 mg/kg dipyridamole, the average dose used in clinical studies, causes a significant increase in myocardial blood flow in zones perfused by normal coronary arteries but only a slight increas...

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Dipyridamole combined with exercise for thallium-201 myocardial imaging.

A new stress test for thallium-201 myocardial imaging in which pharmacological coronary vasodilatation with dipyridamole is combined with dynamic exercise is described. In 38 patients with coronary artery disease the sensitivity, total number of defects, degree of redistribution, and visual quality of thallium-201 imaging were greater after dipyridamole with exercise testing than after exercise...

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Dipyridamole Thallium Imaging

Thallium e01 Tl) myocardial perfusion imaging with exercise is widely accepted as a simple and safe method to diagnose coronary artery disease (CAD) or to evaluate the extent and significance of disease in patients with known CAD. A significant number of patients cannot achieve the necessary level of exercise with routinely performed 201 Tl treadmill or bicycle exercise testing to properly allo...

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Thallium-201 Myocardial Perfusion Imaging

The sensitivity of myocardial perfusion imaging (MPI) using thallium-201 injected both at rest and during peak exercise was compared to simultaneously recorded 12 lead electrocardiography (ECG) for the detection of transient ischemia in 20 normal subjects and 63 patients with coronary artery disease (CAD). No significant perfusion defects or ECG changes were seen on either the rest or exercise ...

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The safety of intravenous dipyridamole thallium myocardial perfusion imaging. Intravenous Dipyridamole Thallium Imaging Study Group.

Clinical data on 3,911 patients were collected from 64 individual investigators to evaluate the safety of intravenous dipyridamole-thallium imaging as an alternative to exercise thallium imaging for the evaluation of coronary artery disease. There were two deaths because of myocardial infarctions, two nonfatal myocardial infarctions, and six cases of acute bronchospasm. Chest pain occurred in 7...

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ژورنال

عنوان ژورنال: Circulation

سال: 1990

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.81.4.1425